8

A 14 year old boy has been recently diagnosed as cystic fibrosis.

A. It is due to gain-of-function mutation in CFTR gene

B. A defect occurs in chloride pumps in most tissues

C. Chymotrypsin may have a therapeutic role

D. Chloride blood test is recommanded for the diagnosis

E. Acute abdominal pain should always be investigated with serum amylase