A heavy drinker came to the clinic with the problem of bilateral breast enlargement. The ultrasound (abdomen) revealed cirrhotic changes in his liver. Which biochemical change is responsible for his symptom?
A. Disturbance in oxidation and conjugation of steroid hormones
B. Disturbance in reduction and conjugation of steroid hormones
C. Vasoactive action of estrogen
D. Alcohol-induced toxic effect on fibrofatty tissues
E. Raised ammonia disturbing cerebral Kreb's cycle
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