10

A stroke patient was recommended to take citacholine by the neurophysican. Citacholine (Cytadine diphosphate choline) provides both choline and cytidine in the the brain.

A. Choline can be used for synthesis of phosphoglycerolipid

B. Acetyl choline formed from choline can be oxidized via Kreb's pathway

C. Acetyl choline formed from choline can be used to replenish glucose

D. Choline can be demethylated to form serine

E. Choline can be deaminated to form ethanolamine

9

A 9 month old baby was diagnosed as methemoglobinemia after having repeated diarrhea. Bottle feeding has been practiced since birth but there was no similar attack before. The water source was said to be from an old private well.

A. Oxygen hemoglobin dissociation curve shifts to right

B. The affinity of hemoglobin for oxygen declines

C. Methylene blue can be the cause

D. Cherry red appearance is the typical presentation

E. Enteric bacterial action on nitrate metabolism may have a role

8

A 14 year old boy has been recently diagnosed as cystic fibrosis.

A. It is due to gain-of-function mutation in CFTR gene

B. A defect occurs in chloride pumps in most tissues

C. Chymotrypsin may have a therapeutic role

D. Chloride blood test is recommanded for the diagnosis

E. Acute abdominal pain should always be investigated with serum amylase 

7

A heavy drinker came to the clinic with the problem of bilateral breast enlargement. The ultrasound (abdomen) revealed cirrhotic changes in his liver. Which biochemical change is responsible for his symptom?

A. Disturbance in oxidation and conjugation of steroid hormones
B. Disturbance in reduction and conjugation of steroid hormones
C. Vasoactive action of estrogen
D. Alcohol-induced toxic effect on fibrofatty tissues
E. Raised ammonia disturbing cerebral Kreb's cycle

6

After taking a long flight, 65 year old previously healthy lady became breathless and collapsed. The ECG proved of tachycardia and SI QIII TIII pattern. Which is the best answer for her pathobiology?

A. Respiratory acidosis
B. Respiratory alkalosis
C. D-dimer which is derived from prothrombin may be helpful for diagnosis
D. Oxidation of Vit K should be prevented by warfirin
E. Type 2 respiratory failure

5

A 72 year old man came to the emergency department by the complaint of central chest pain for about 2 hours. He was suspected of suffering from acute coronary syndrome. Which of the following cardiac markers is the gold standard for the diagnosis?

A. LD1
B. Cardiac troponin
C. AST
D. Myoglobin
E. CK MB

4

A 72 year old man with the diagnosis of myocardial infarct suffers from central chest pain on the 6th day of admission. ECG changes are difficult to be interpreted for differentiation between the old infarct and a suspected new event. Which of the following cardiac enzymes may be useful for the diagnosis of myocardial reinfarction?

A. LD1
B. Cardiac troponin-I
C. AST
D. Myoglobin
E. CK MB